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Genomics 3.0: Synthetic Functional Enzymes Created Online

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2008-03-21 06:21:10 by Michael in Medgadget
...enzymes never seen in nature. For the enzyme design project, Baker's team [David Baker, HHMI Investigator and Professor of Biochemistry at the University of Washington, Seattle --ed.] , led by senior fellows Daniela Rothlesberger and Eric Althoff and graduate students Lin Jiang and Alex Zanghellini, designed active sites they thought would...
 
Tags: enzymes, enzyme design project, team david baker, baker, enzyme, amino acid sequences, fold, speed 200-fold, active sites
 
 
 
 
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Darwinian Evolution on a Chip

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2008-04-08 08:00:39 by Tim in Medgadget
...enzymes to demonstrate adaptation to changing environmental conditions From the authors' summary: Laboratory evolution is greatly accelerated compared with natural evolution, but it usually requires substantial manipulation by the experimenter. Here we describe a system that relies on computer control and microfluidic chip technology to...
 
Tags: evolution, chip, natural evolution, rna enzymes, enzymes, population, microfluidic chip technology, laboratory evolution, real time
 
 
 
 
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MIT Student Invents Effective Bacteriophage

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2008-02-28 08:45:25 by Michael in Medgadget
...enzymes, which must be administered systemically and are costly. Medical devices infected by biofilms, such as replacement hip joints or pacemakers, often have to be removed surgically Lu invented enzymatically-active bacteriophage that directly target the infection site, where they can simultaneously penetrate the biofilm's protective slime...
 
Tags: bacteriophage, bacteria beware, bacteria, kill food-borne bacteria, treatment, bacteriophage carries dna, current treatment methods, natural bacteriophage, drug resistant bacteria
 
 
 
 
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Laundry Dropps

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2008-04-01 13:22:18 by HASH0x8bb6684 in Cool Hunting
...enzymes. A lack of enzymes also keeps colors looking brighter longer. The portability not only makes trips home from the supermarket and to the laundromat easier, but the reduction is packaging is pretty dramatic (about 300x less plastic) and the reduced weight and bulk cuts down on fuel and delivery boxes The pods are septic-friendly,...
 
Tags: laundry dropps, -free, laundry dropps start, free, detergent pods, detergent, dye-free version, pods, clean
 
 
 
 
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Laundry Dropps

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2008-04-01 18:22:18 by Ami Kealoha in Cool Hunting
...enzymes. A lack of enzymes also keeps colors looking brighter longer. The portability not only makes trips home from the supermarket and to the laundromat easier, but the reduction is packaging is pretty dramatic (about 300x less plastic) and the reduced weight and bulk cuts down on fuel and delivery boxes The pods are septic-friendly,...
 
Tags: laundry dropps, -free, laundry dropps start, free, detergent pods, detergent, dye-free version, pods, clean
 
 
 
 
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Rapid Sequencing May Lead to "Personalized" Vitamins

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2008-06-09 21:30:25 by jhbarad in Medgadget
...enzymes in the human genome. Many dysfunctional variants can be corrected with specific vitamins such as Folate for methylenetetrahydrofolate reductase (MTHFR). Here is some more info from the press release: Using DNA samples from 564 individuals of many races and ethnicities, colleagues at Applied Biosystems of Foster City, Calif., sequenced...
 
Tags: mthfr enzyme, enzyme, variants, uncommon variants, berkeley scientists, enzyme activity, berkeley, common variants, harmful mutations
 
 
 
 
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Stichelton is the new Stilton

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2008-01-01 12:01:00 by bookofjoe in bookofjoe
...enzymes from calves stomachs rather than factory-grown molds. To create a delicate structure, he adds very small doses of starter bacteria and rennet, then ladles curds by hand into a trough where they mature slowly overnight. And he doesnt wrap the cheeses in plastic, so yeasts and bacteria can create an outer rind and add flavor In...
 
Tags: stichelton, cheese, cheeses, stilton-like cheeses, traditional cheese, stilton, quality, cheese quality, milk
 
 
 
 
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Ewww....Sperm Could Power Nanobots

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2008-01-03 08:03:18 by Josh in Medgadget
...enzymes and performing other medical roles within a patient's body fter tethering the first two proteins in the pathway to the chip, the researchers found that both did well in breaking down glucose and handing the end-product to the next protein. Compared to versions lacking a surface-targeting domain and "just randomly glommed" onto a...
 
Tags: nanobots, assembly line, tiny assembly line, future, future nanobots, pathway, tiny medical devices, biological pathway, preliminary research report
 
 
 
 
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'Proust Was a Neuroscientist'

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2008-01-27 12:01:00 by bookofjoe in bookofjoe
...enzymes, you're missing something Wired: Which artists are making the discoveries of tomorrow Lehrer: Maybe my next book will be "Kanye West Was a Neuroscientist." He's making use of the same musical principles as Beethoven, the same idea of building toward a pattern but then denying the listener that pattern by injecting randomness, because...
 
Tags: author jonah lehrer, lehrer, proust, lehrer argues, jonah lehrer, wired, wired magazine interview, marcel proust, artists
 
 
 
 
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"Unnatural Base Pairs" Added to DNA

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2008-01-30 16:44:03 by Josh in Medgadget
...enzymes that replicate DNA inside cells Random generation Frustrated by the slow pace designing and synthesising potential new bases one at a time, Romesberg borrowed some tricks from drug development companies. The resulting large scale experiments generated many potential bases at random, which were then screened to see if they would be...
 
Tags: base pair, real base pair, unnatural, unnatural base pair, dna, pair, base pairs, dna amplification, romesberg